Principal Scientist and Consultant, Novartis AG

PhD in Life Sciences

Thesis title: ”Modeling of Calcium Homeostasis in the Rat and its Perturbations”. Building of a mathematical model describing calcium homeostasis, including its analysis and simulation of pathologies. Advisors: Dr. Aurélie Edwards and Pr. Olivier Bonny.

Université Pierre et Marie Curie, Paris, Université de Lausanne, Switzerland

2013-2016

Master’s Degree in Ecosiences, MIV

Main subjects: Mathematics, Theoretical Ecology and Programming.

Université Claude Bernard (UCBL), Lyon

2011-2013

Licence (3 year degree) in Mathematics and Computer Sciences for the Living (MIV)

Main subjects: Mathematics, Ecology and Computer Sciences.

Université Claude Bernard (UCBL), Lyon

2010-2011

Preparatory School for Engineers

Main subjects: Mathematics, Physics, Biology, Geology.

Lycée Claude Fauriel, Saint Etienne

2008-2010

Post Doctoral Researcher

Software engineer

The Interface Group, University of Zurich (UZH)

06/17 - 06/19

Two main projects:

• develop user-friendly interfaces of Calcium and Phosphate Homeosta- sis, using the R-Shiny package, javascript and C. Management of linux web servers. Design new interactive tools dedicated to teaching courses.
• build a model linking the cardiac and renal functions,to better understand the interplay between chronic kidney disease as well as cardiac failure. Create virtual patient populations using Monte Carlo simulations.

Post Doctoral Researcher

Improvements to the model developed during my doctoral thesis. Publication of a second article (see publications). Supervisors: Dr. Aurélie Edwards and Pr. Olivier Bonny.

CHUV, Lausanne university hospital, Switzerland

01/17 - 03/17

Internship in a Team of Theoretical Physiology

Improvements to the model developed during the previous internship. Supervisors: Dr. Moisés Santillan, Pr. Michael Mackey

Centre for Applied Mathematics in Bioscience and Medicine (CAMBAM), Mc Gill University, Montreal, Canada.

07/13 - 08/13

Internship in a Laboratory of Applied Mathematics

Project title: ”Multiscale modeling of Zebrafish Somitogenesis” Development of a model accounting for the intra-cellular oscillator in each cell during somitogenesis. Supervisors: Dr. Laurent Pujo-menjouet (UCBL), Pr. Michael Mackey (Mc Gill, Canada).

Institut National de Recherche en Informatique et Automatique (INRIA), Team Dracula, Lyon

01/13 - 07/13

Contacts

Dr. Aurélie Edwards
Pr. Olivier Bonny. +41 21 692 53 60
Dr. Laurent Pujo-Menjouet. +33 472 431 008
Dr. Diane de Zélicourt. +41 (0) 44 635 50 56
Pr. Vartan Kurtcuoglu. +41 (0) 44 635 50 55

R packages

Develop outstanding {shiny} apps for iOS, Android and desktop.

Bootstrap 4 shinydashboard using AdminLTE3.

Internship in a Laboratory of Applied Mathematics

Project title: ” Mathematical modeling of somitogenesis, reaction- diffusion systems”. Analysis of two mathematical models: cell-cycle and clock/wavefront models. Supervisor: Dr. Laurent Pujo-Menjouet (UCBL).

Institut National de Recherche en Informatique et Automatique (INRIA), Team Dracula, Lyon

03/12 - 07/12

Internship in a Laboratory of Theoretical Ecology

Project title: ” Ecotoxicology of Daphnia Magna ”. Study of the impact of pollution on the growth of Daphnia Magna through mathematical models. Supervisors: Pr. Sandrine Charles (UCBL), Pr. Marie Laure Delignette Muller (Ecole Nationale Vétérinaire de Lyon).

Laboratoire de Biométrie et Biologie Evolutive (LBBE), Team Modélisation et Ecotoxycologie Prédictive (MEPS), Lyo

06/11 - 08/11

An eLearning platform to teach calcium and phosphate homeostasis

Submitted to American Journal of Physiology-Advances in Physiology Education.

N/A

2019

D. Granjon, O. Bonny, F. Verrey, V. Kurtcuoglu and D. de Zelicourt.

Coupling between Phosphate and Calcium Homeostasis: A Mathematical Model

American Journal of Physiology-Renal Physiology, 313(6): F1181-F1199. doi: 10.1152/ajprenal.00271.2017

N/A

2017

D. Granjon, O. Bonny, A. Edwards.

A Model of Calcium Homeostasis in the Rat

American Journal of Physiology-Renal Physiology, 311 (5): F1047-F1062. doi: 10.1152/ajprenal.00230.2016

N/A

2016

D. Granjon, O. Bonny, A. Edwards.

Outstanding User Interfaces with Shiny

This book provides the necessary knowledge to extend Shiny’s layout: https://divadnojnarg.github.io/outstanding-shiny-ui/.

N/A

2020

D. Granjon

satRdayNeuch 2020

Oral presentation: An introduction to shinyMobile: https://github.com/DivadNojnarg/satRdayNeuch2020.

Remote (Covid 2019)

14/03/2020

Zurich R User Group

Oral presentation: "shinyMobile: Build Native Looking Shiny Apps: https://rinterface.com/shiny/talks/zurichR2020/index.html#slide=1.

Zurich

29/01/2020

BaselR

Oral presentation: "Development of a web application to represent models of calcium and phosphate homeostasis using R.

Basel

05/12/2019

Shiny Developers Series

Podcast interview: "Production-ready UIs for Shiny: https://shinydevseries.com/post/episode-4-rinterface/.

Online

08/2019

useR 2019

Poster presentation: "A Shiny Powered Virtual Patient: https://github.com/DivadNojnarg/userR2019.

Toulouse

09/07/19 - 12/07/19

Zurich R User Group

Oral presentation: "RinteRface, Production-ready UIs for Shiny: https://rinterface.com/shiny/talks/zurichR2019/index.html#slide=1.

Zurich

27/05/19

NCCR Kidney.CH Retreat 2019

Oral presentation: ”Web applications for physiology: bridge the gap between research and teaching”.

Murten, Switzerland

31/01/19 - 01/02/19

NCCR Kidney.CH Summer School 2018

Poster first author: ”Web-based e-learning tools of Calcium and Phosphate Homeostasis”.

Zurich, Switzerland

09/09/18 - 12/09/18

World Congress of Biomechanics 2018

Poster first author: ”Addressing biomedical diversity via eLearning, an example from a physiology curriculum”.

Dublin, Ireland

08/07/18 - 12/07/18

NCCR Kidney.CH Retreat 2018

Poster first author: ”A web-based application of Calcium and Phosphate Homeostasis”.

Murten, Switzerland

01/02/18 - 02/02/18

Bachelor–Themenworkshops 5. Semester HS 2017

Oral presentation: Computational Physiology.

Zurich University of the Arts, Switzerland

17/10/17

Meeting of the Federation of Physiological Societies and the French Physiological Society

Poster presentation: ”Role of the rapidly exchangeable calcium pool in bone in calcium homeostasis”.

Centre de Recherche des Cordeliers, Paris

29/06/16 - 1/07/16

Annual Franco-Swiss Meeting on Electrolytes Metabolism and Renal Physiology

Oral presentation: ”A model of Ca/Pi homeostasis in the Rat”.

Inselspital, Bern

23/03/16 - 24/03/16

NCCR Kidney.CH Retreat 2016

Poster first author: ”Role of the bone rapidly exchangeable calcium pool in calcium homeostasis”.

Murten, Switzerland

25/02/16 - 27/02/16

Société Francophone de Dialyse/Société de Néphrologie

Poster first author: ”Consequences of primary hyperparathyroidism on renal calcium excretion”.

Lyon, France

29/09/15 - 02/10/15

Annual Franco-Swiss Meeting on Electrolytes Metabolism and Renal Physiology

Oral presentation: ”A Model of Calcium Homeostasis in the Rat”.

Centre de Recherche des Cordeliers, Paris

19/03/15 - 20/03/15

Annual Franco-Swiss Meeting on Electrolytes Metabolism and Renal Physiology

Oral presentation: ”A Simplified Model of Plasma Calcium Regulation by PTH”.

CHUV, Lausanne

19/03/14 - 20/03/14

Conference " In honour of Michael Mackey’s 70th birthday

Oral presentation: ”Oscillatory dynamic during zebrafish somitogenesis”.

Lyon, France

3/06/13 - 6/06/13

2019 RStudio Shiny Contest

• Runner-Up price: A Virtual Lab for Teaching Physiology.

N/A

Link: https://community.rstudio.com/t/shiny-contest-submission-a-virtual-lab-for-teaching-physiology/25348

2019

NCCR Kidney.CH Retreat 2018

• Best Poster Award, 2nd price: A web-based application of Calcium and Phosphate Homeostasis.

N/A

N/A

2019